The Missions menu holds 56 missions: 35 award missions, 1 StreetPass supply mission (template), 1 StreetPass WANTED mission (template), 14 kill missions and 5 StreetPass infection missions. In the StreetPass missions the game fills in placeholders such as [player] with the player you passed.
Award missions (35)
| Mission | Requirement | Reward |
|---|---|---|
| Chapter 1 | Clear Episodes 1 - 3 | Raid Mode Stages 1 to 7 unlocked |
| Chapter 2 | Clear Episodes 4 - 6 | Raid Mode Stages 8 to 12 unlocked; New outfit |
| Chapter 3 | Clear Episodes 7 - 9 | Raid Mode Stages 13 to 17 unlocked |
| Final Chapter | Clear Episodes 10 - 12 | Raid Mode Stages 18 to 20 and Bonus Stage; HELL difficulty unlocked |
| CASUAL Cleared | Clear CASUAL difficulty or higher | Custom Parts Charge Shot 3 (For campaign use) |
| NORMAL Cleared | Clear NORMAL difficulty or higher | Shotgun Hydra (For campaign use) |
| HELL Cleared | Clear HELL difficulty | Infinite Rocket Launcher (For campaign use) |
| Aloof Challenger | Clear CASUAL difficulty or higher without using herbs or the Infinite Rocket Launcher | Custom Parts Auto Loader (For campaign use) |
| Secret Sign 1 | Scan 1 hidden hand print | Green Herb (For campaign use) |
| Secret Sign 15 | Scan 15 hidden hand prints | Rifle PSG1 (For campaign use) |
| Secret Sign 30 | Scan 30 hidden hand prints | Handgun G18 (For campaign use) |
| Dodge Master | Dodge 20 times | Custom Parts Bind 1 (For campaign use) |
| Angry Fist | Land 10 fully charged physical attacks | Custom Parts Long Magazine 2 (For campaign use) |
| Researcher | Scan all enemies | Custom Parts Edge Runner 2 (For campaign use) |
| B.O.W. Hunter | Defeat 150 enemies | Handgun PC356 (For campaign use) |
| CHASM Cleared | Clear all stages in Raid mode on CHASM | Raid Mode TRENCH difficulty unlocked; New outfit |
| TRENCH Cleared | Clear all stages in Raid mode on TRENCH | Raid Mode ABYSS difficulty unlocked; New outfit |
| ABYSS Cleared | Clear all stages in Raid mode on ABYSS | New outfit |
| CHASM: All Cleared, S Rank | Clear all stages in Raid mode on CHASM, S Rank | Honor - Color 1 |
| TRENCH: All Cleared, S Rank | Clear all stages in Raid mode on TRENCH, S Rank | Honor - Color 2 |
| ABYSS: All Cleared, S Rank | Clear all stages in Raid mode on ABYSS, S Rank | Honor - Color 3 |
| Ghost Ship 100% Cleared | Find the real goal area in the ship | New outfit |
| Level 5 | Reach player level 5 | New outfit |
| Level 10 | Reach player level 10 | New outfit |
| Level 20 | Reach player level 20 | New outfit |
| Level 30 | Reach player level 30 | New outfit |
| Level 40 | Reach player level 40 | New outfit |
| Level 50 | Reach player level 50 | New outfit |
| Legendary Weapon | Obtain a super rare weapon | New outfit |
| Legendary Raider | Obtain all super rare weapons | New outfit |
| 50 Missions | Complete 50 missions | New outfit |
| 100 Missions | Complete 100 missions | New outfit |
| 200 Missions | Complete 200 missions | 100000 BP |
| 500 Missions | Complete 500 missions | Random Weapon Lineup +1 |
| 1000 Missions | Complete 1000 missions | Random Parts Lineup +1 |
StreetPass supply mission (template) (1)
| Mission | Requirement | Reward |
|---|---|---|
| Supplies from [player] LvN | I'm sending you these supplies in hopes that you're still alive. | - |
StreetPass WANTED mission (template) (1)
| Mission | Requirement | Reward |
|---|---|---|
| WANTED: [player] LvN | If by any chance you find me turning into one of those things, please put me out of my misery. I'm in [stage] ([difficulty]). | - |
Kill missions (14)
| Mission | Requirement | Reward |
|---|---|---|
| Defeat Ooze | Once human, living corpses... Defeat 20 of them. | 10000 BP |
| Defeat Infected Rachael | An FBC agent who was infected. Put her out of her misery. | 10000 BP |
| Defeat Sea Creeper | Repulsive shadows in the water. Defeat 5 of them. | 10000 BP |
| Defeat Fenrir | Biological weapons based on wolves. Defeat 20 of them. | 10000 BP |
| Defeat Ghiozzo | Ugly and deformed giant fish. Defeat 15 of them. | 10000 BP |
| Defeat Hunter | Mass produced reptilian B.O.W.s. Defeat 20 of them. | 20000 BP |
| Defeat Farfarello | You won't be able to find these creatures with your eyes. But if you have the skill, you should be able to take down 5 of them. | 25000 BP |
| Defeat Scarmiglione | An evil creation with a lance and shield. Defeat 10 of them. | 30000 BP |
| Defeat Globster | An ugly chunk of meat from the beach. Defeat 10 of them. | 10000 BP |
| Defeat Skagdead | A giant bulge of rotten flesh. Expect to be split in two if you are caught. Just make sure to kill 5 of them before you are. | 35000 BP |
| Defeat Draghignazzo | A giant, disfigured creature with a shell that can deflect bullets. Kill 5 of them. | 40000 BP |
| Defeat Final Form Abyss | King of the abyss who can control powerful phantoms. Take him out. | 40000 BP |
| Defeat Dark Ooze | A strange meat doll who wears robes of darkness. Take down 10 of them. | 10000 BP |
| Defeat Baby Draghignazzo | The youngling of a giant shelled creature. Small but dangerous. Kill 5 of them. | 30000 BP |
StreetPass infection missions (5)
| Mission | Requirement | Reward |
|---|---|---|
| Infection: T-Virus | StreetPass with 10 people. | - |
| Infection: G-Virus | StreetPass with 20 people who have an "Infection" mission. | - |
| Infection: T-Veronica | StreetPass with 8 people who have the same mission. | - |
| Infection: T-Abyss virus | StreetPass with 10 people who have an "Infection" mission. | - |
| Infection: Progenitor | StreetPass with 4 people who have the same mission. | - |